Genomic Characterization Scientist

Eagle Health is seeking a Genomic Characterization Scientist to join our team in Fort Detrick, MD.

The Scientist shall provide laboratory and scientific support within the Center for Genome Sciences (CGS) to cover CGS Genomic Characterization capabilities. The employee shall conduct research investigations centered on Molecular Biology, Antimicrobial Resistance (AMR), Immunology, Genetics, and/or Biochemistry or similar field. They will perform laboratory experiments/protocols directed by CGS PIs and Supervisors.

• To perform molecular protocols and technologies to identify microbiological pathogens, characterize pathogenesis mechanisms of BSATs and study the host immune response.
• To provide expertise in epitope mapping on polyclonal humoral responses to pathogen using phage domain programmable arrays, B cell receptor (BCR) repertoire characterization in vaccinated or infected animals or human subjects, and advanced Immunological concepts.
• Development and improvement of animal model important for BSATs. Characterization of animal species genomic background (e.g. MHC expression), development and species specific reagents, and comparative genomic to evaluate the model compared with humans. Generation of agnostic tools to evaluate the animal model and human samples with the same assays.
• To prepare or contribute to technical reports and manuscripts for publication, publicly present data upon request at an average of one conferences per year. Assist in the establishment of extramural collaborations and contracts to augment the research program he or she supports. The employee must show understanding of the progress toward publication as outlined by the TPOC/COR to include their efforts to obtain and format data and research methods, within a reasonable timeframe suitable for that research project and given support. A Lab Progress Report should be submitted monthly. An acceptable alternative format than publication outlines is contribution to Quarterly Reports to funding agencies. The employee shall update Lab Data weekly in a shared continuity folder for all publications/Quarterly Reports that includes all supporting data or directories where data is stored (raw and processed data and sample processing records).
• To oversee the technical work of supporting personnel assigned to the research programs. Specifically to train and ensure SOPs, sample and analytical workflows are followed, tracked, and documented by supporting personnel. Data records are maintained in a current status within reasonable timeframe after sample and analytic processing. Lab Data Records and SOPs are updated upon change with a full description of the change and signature of the PI. Lab SOPs are reviewed and signed semi-annually IAW CGS guidelines.
• To maintain laboratory records documenting sample processing, protocol design and usage, and data management that meet current CGS and Institutional requirements and ensure continuity and collective-sharing of resources. Communicate to the PI or assigned supervisor(s) experimental data, laboratory issues or other work-related issues. Workflows and SOPs shall be reviewed and signed IAW CGS policy on a semi-annual basis or as determined by CGS before being implemented.
• To maintain laboratory records documenting sample processing, protocol design and usage, and data management that meet current CGS and Institutional requirements and ensure continuity and collective-sharing of resources. Communicate to the PI or assigned supervisor(s) experimental data, laboratory issues or other work-related issues. Workflows and SOPs shall be reviewed and signed IAW CGS policy on a semi-annual basis or as determined by CGS before being implemented. Employee shall assist in maintaining laboratory equipment, specimens and reagents inventories, as well as keeping an organized, safe and professional work environment.
• Under special circumstances, the employee may require variable work schedules (second shift) and occasional weekends in order to accomplish time sensitive laboratory tasks.
• Participate in all activities pertinent to lab performance and safety, including weekly lab clean up to avoid contaminations, be primary, secondary or tertiary point of contact for equipment and/or laboratory spaces (POC will be contacted by phone during emergencies, such as alarms or lost of power, and need to respond according to emergency plan for the CGS). Contact commercial company and/or agencymedical maintenance, Clinical Engineering (CEB) when an instrument is malfunctioning or needs periodical PM, and escort engineers during the scheduled visit(s) at the agency. Ensure reagents in the lab are not expired and ordered periodically to avoid shortage in reagents and stops in processes. Maintain reagent, sample, and intermediary processes products inventory updated and stored in the designated areas, following biosafety guidance's and CGS protocols. Receive and appropriately storage reagents and samples delivered to the CGS.