New

Postdoctoral Research Fellow, Anesthesiology

Massachusetts General Hospital
United States, Massachusetts, Boston
60 Blossom Street (Show on map)
Jul 28, 2025
TO APPLY, please submit your CV and a letter of interest to Abigail Pascarelli at apascarelli1@mgh.harvard.edu The Department of Anesthesiology at Mass General Brigham is seeking a Postdoctoral Research Fellow to conduct basic research in studying the biology of postoperative delirium and related cognitive dysfunction. The position focuses on applying molecular approaches, including proteomics, transcriptomics, and DNA sequencing, to explore the underlying mechanisms of neuronal injury and immune-neural interactions. The fellow will be responsible for designing and conducting bench experiments using neuronal cell culture models and molecular biology techniques. Experimental methods may include qPCR, RNA sequencing, Simoa assays, laser confocal microscopy, flow cytometry, and related tools. In addition to laboratory work, the fellow will analyze and present data, contribute to the preparation of manuscripts and grant applications, and coordinate research activities with collaborators. Strong organizational skills, close attention to detail, and clear communication are essential. The ideal candidate should be capable of working independently while also contributing effectively to a team-based research environment. To apply, please submit your CV and a letter of interest to Abigail Pascarelli at apascarelli1@mgh.harvard.edu With supervision and guidance, responsibilities of the Postdoctoral Research Fellow will include: Performs independent and highly specialized experimental procedures Designs and implements modifications of research protocols Troubleshooting problems and instructing colleagues in highly specialized techniques Synthesizes and interprets results Performs advanced data recording and analysis using various software programs and statistical techniques Maintaining organized and detailed records of laboratory experiments in electronic laboratory notebooks Presentation of results at lab meetings and national conferences Preparation and submission of research manuscripts to peer-reviewed journals Assisting with preparation of grant applications Other duties as assigned EDUCATION: PhD or MD required in neuroscience, biomedical engineering, molecular biology, biochemistry, cell biology, or a related field. EXPERIENCE: Prior lab experience required. Must have evidence of strong scientific productivity, including peer-reviewed publications. Open to highly motivated candidates with a relevant background. Secondary appointment will be at Harvard Medical School. SUPERVISORY RESPONSIBILITY Assistance guiding research technicians and trainees in the lab is expected. WORKING CONDITIONS: Work will be performed in a fast-paced research laboratory environment, requiring teamwork, collaboration, and flexibility. Must be able to work independently. A successful candidate will: Work independently under general direction of the Principal Investigator Be motivated, meticulous, organized, and detail-oriented Demonstrate initiative and enthusiasm for learning new techniques Have strong analytical and problem-solving skills Possess strong technical abilities and computer science skills Possess exceptional written and oral communication skills as demonstrated by publications and presentation Possess the ability to make independent and effective decisions in a timely fashion Possess competence in research techniques and methodologies Have excellent interpersonal skills Be a team player who works well with other lab members The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.