Senior Research Technician

The Department of Neuroscience is a basic research department focusing on synaptic biology and glia biology. The lab of Dr. Dulla investigates how synapses are formed and remodeled in the developing nervous system with a broad focus on neurological disease and epilepsy. We address this question in mouse models and apply electrophysiological and imaging approaches, together with mouse behavioral and in vivo electrophysiological studies.

The successful candidate will work directly with the Principal Investigator and a team to study the neurological effects of brain infection. The role involves working on understanding how the brain gets infected with tuberculosis (TB) and how varying outcomes are driven by the brain's immune response. There are three primary tasks in this position:

1. Carry out TB infections in the brains of mice to understand the effects of infection on the brain and the immune response. This requires coordination with collaborators and detail-oriented animal surgeries in a BSL-3 environment.
2. Analyze animal outcomes, anatomical data, transcriptional data, and generate publication quality figures demonstrating results, and contribute to writing of reports, manuscripts, and presentations. Analyzing single cell and/or single nuclei RNAseq data could be a component.
3. Play a supportive role in the lab, contribute to general lab maintenance (ordering supplies, maintaining equipment, scheduling), and work with graduate students, post-docs, and research scientists to support their ongoing projects.

• Mouse care, animal surgery, tissue collection and preparation
• Analyze data, generate publication quality figure, and contribute to the writing of reports
• Ordering, lab maintenance, and supporting others in their research

Basic Requirements:

• Knowledge and skills as typically acquired through Bachelor's degree in science
• At least three years of related laboratory experience
• Extensive experience with animal work and survival surgery
• Strong computer and database/spreadsheet skills
• Applicants need to be highly organized and have excellent communication skills
• Highly organized with attention to detail/follow-up
• Able to communicate with others effectively

Preferred Qualifications:

• Advanced knowledge and experience with laboratory techniques and procedures
• Knowledge of neuroscience
• Knowledge of immunology and microbiology
• Experience working in a BSL-3 environment
• Strong understanding of statistics