Chief of Staff and Director of Squad Operations and Administration - Foundational Products

Why Genentech

In 1976, a ten-minute conversation over beer stretched into three hours and birthed an industry. As Genentech celebrates its fiftieth anniversary in 2026, we are not merely looking back at "the biotech company that started it all"; we are architecting the engine that makes the mission possible.

The Foundational Products (FP) Squad and Network is the bedrock of this legacy, managing the essential portfolio that funded our past and fuels our future. FP is the organizational "anchor," managing a diverse portfolio consisting of 17 products. In 2025 alone, this network increased organizational impact and successfully provided medicine to nearly 300,000 patients.

The Opportunity

As Chief of Staff & Director, Operations and Administration for the Foundational Products Squad, you will serve as a strategic partner and operational leader at the heart of our mission. This role is positioned as a senior "understudy" to the VP-a high-level proxy capable of managing the immediate complexity of the US business while building future global connectivity.

You will touch the full product value chain and lifecycle, including access and contracting, CSO support, in-line marketing, and potential partnership with Global on biosimilar strategy, divestments and discontinuations. You will drive the squad's business planning, operational excellence, and cross-functional communications, ensuring our network remains aligned, agile, and positioned for impact.

As a key member of the Commercial Portfolio Organization (CPO) Operations and Administration Leadership Team, you will help shape how talent is developed and deployed. You will lead a stellar team of Operations and Administrative professionals, driving a rigorous delegation process that empowers them to handle operations so you can focus on high-value strategic synthesis.

Our work is defined by four strategic pillars: driving commercial success, strategic commercialization, expanding patient access, and cultivating top talent. We are experts at delivering for patients across Genentech's core portfolio while positioning the organization for future growth in an evolving landscape.

• Strategic Partnership & Advisory: Serve as a high-level "Deputy" and proxy for the VP by synthesizing complex cross-functional insights (Legal, Medical, Marketing, etc.) to drive decision-making, while acting as a trusted sounding board empowered to challenge leadership and ensure strategic alignment across the network.

• Operational Excellence & Squad Health: Drive the "Rhythm of the Business" across multiple squads by leading high-impact milestones and Quarterly Business Reviews (QBRs), while maintaining accountability for overall squad health and championing the integration of Everyday AI and modern work practices to optimize global operations.

• Cross-Functional Leadership & Narrative Stewardship: Lead the narrative for the VP by drafting core strategic communications that inspire stakeholders, while navigating the organization through complex change and fostering a connected, humanized culture that prioritizes meaningful collaboration over transactional tasks.

• Team Leadership & Talent Development: Lead and develop a high-performing team of three while collaborating across the CPO leadership team to strategically deploy talent and resources in alignment with the evolving needs of a multi-billion-dollar portfolio.

• Business & Financial Acumen: Facilitate critical discussions around ROI, P&L, and resource trade-offs to drive data-driven investment decisions, while representing squad priorities with senior leadership to influence outcomes through strong executive presence.

Who You Are

• Bachelors degree in business, science, communications, or other relevant field.

• 10+ years of work experience in operations, communications, or marketing within the pharmaceutical or biotech industry.

• Strategic Operator: experienced in operational discipline and strategic field insight, combining a history of field sales leadership with home-office operations experience to act as a thought partner to senior executives in complex, changing environments.

• Global Connector & Narrative Architect: strong storytelling skills with the "global fluency" to lead across cultures and time zones, experience humanizing complex data into inspiring narratives while bridging gaps between the inner leadership circle and rotating cross-functional partners.

• Resilient & Compliant Leadership: An adaptable leader who prioritizes people over rigid processes, backed by an unwavering commitment to corporate policy and specific 2026 California legislative standards (including SB 642, SB 294, and AB 692).

This role is located in South San Francisco, CA and offers a hybrid schedule working on campus 3 days per week.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location in California is $166,500 - $309,100. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.