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Principal Analyst, Market Access Tech

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Jan 27, 2026

Job Description

General Summary

The Market Access Technical Lead will oversee technical operations for Vertex's global revenue management platforms, including ModelN Flex and ModelN Global Pricing Management. This role ensures system integrity, optimizes technical workflows, and partners cross-functionally to support pricing strategies and compliance in a dynamic, global environment.

Key Duties and Responsibilities

  • Lead technical operations and configuration management for ModelN Flex and Global Pricing Management systems.
  • Subject matter expertise on Chargebacks, Government Pricing, Medicaid, Commercial Rebates, 340B Validations, Membership Management
  • Serve as the primary technical liaison between DTE, ModelN, and Application Service Providers for system enhancements and issue resolution.
  • Oversee system integrations, data flows, and ensure compliance with global pricing and revenue management standards.
  • Develop and maintain technical documentation, SOPs, and governance frameworks for system operations.
  • Drive continuous improvement initiatives to enhance system performance and user experience.
  • Manage technical aspects of system upgrades, testing, and validation activities.
  • Provide technical guidance and training to internal stakeholders on system functionality and best practices.
  • Monitor system performance metrics and proactively address potential risks or gaps.

Knowledge and Skills

  • Expertise in ModelN Flex and ModelN Global Pricing Management platforms
  • Strong understanding of pharmaceutical pricing, market access, and revenue management processes.
  • Proficiency in system configuration, data integration, and troubleshooting.
  • Excellent analytical, problem-solving, and project management skills.
  • Ability to communicate complex technical concepts to non-technical stakeholders.
  • Familiarity with compliance requirements in global pricing and revenue management.
  • Strong knowledge of key datasets stored and managed by Market access systems and ability to extract and analyze them as per business need
  • Strong knowledge of HRSA datasets like Medicaid Exclusion File, Covered Entities, Pharmacy Services etc
  • Hands on experience working on Oracle databases/Snowflake and query languages like SQL is required.
  • Experience in supporting data integrations and ETL is required.
  • Experience in advanced reporting using IBM Cognos

Education and Experience

  • Bachelor's degree in Computer Science, Information Systems, Engineering, or related discipline.
  • Typically requires 7+ years of experience in technical operations or systems management within pharmaceutical or biotech industry.
  • Hands-on experience with ModelN platforms is required.
  • Prior experience in market access or revenue management systems is required

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Pay Range:

$0 - $0

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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