New

Computational Scientist- Mootha Laboratory

Broad Institute
paid time off, paid holidays, 401(k), retirement plan
United States, Massachusetts, Cambridge
Feb 13, 2026
Description & Requirements Computational Scientist - Mootha Laboratory Join the Mootha Laboratory at HHMI/Broad Institute to uncover the mechanisms of mitochondrial dysfunction in human disease. As a Ph.D. Data Scientist, you will join a dynamic team of ~25 post-docs and professional scientists dedicated to high-impact discovery. Your role will involve analyzing and integrating high-dimensional multi-omics data (DNA sequencing, RNA-seq, single cell RNA-seq, proteomics, and metabolomics). You will work closely with lab members to influence all aspects of a project's lifecycle, from initial experimental design and data capture, to quality control, statistical inference, and biological interpretation. As part of the Broad Institute, you will have access to world-class computational infrastructure and a vibrant community of over 500 scientists. This is a rare opportunity to be part of an exciting team of leaders in biochemistry, computational biology, and clinical medicine, with ample opportunities for co-authorship on high-impact publications. REQUIREMENTS: Education: Ph.D. in Bioinformatics, Computational Biology, Computer Science, Mathematics or related quantitative field Experience: 3+ years of research experience (inclusive of doctoral training) with a proven track record of applying multivariate statistics and integrative approaches to complex biological datasets Technical skills: Deep expertise in scientific programming (e.g. R or Python); experience with cloud computing (e.g. GCP/AWS/Terra.bio) and reproducible research practices is preferred Communication: Excellent oral and written communication skills, with the ability to translate statistics and complex data findings into actionable biological insights for experimental collaborators Track record in Computational Biology, as evidenced by a first-author paper in Computational Biology The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.