New

Research Scientist

California Institute of Technology
vision insurance, parental leave, paid time off, sick time, tuition reimbursement
United States, California, Pasadena
Apr 16, 2026
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary We are seeking a research scientist to conduct research to understand the histone-to-protamine transition and chromatoid body formation during spermiogenesis. Essential Job Duties Design and establish an in vitro system in somactic cell lines to recapitulate the histone-to-protamine transition (20%) Execute and analyze genome-wide CRISPRi screents to identify factors involved in the histone-to-protamine transition in somatic cell lines (30%) Apply molecular biology approaches to characterize the molecular composition of the chromatoid body and investigate its assocation with the nucleus (20%) Collaborate with team members and other research groups to address technical challenges affecting experimental outcomes and related research (15%) Prepare research reports and presentations for internal meetings, publications, and scientific conferences (15%) Basic Qualifications PhD in biological sciences Five years of postdoctoral research experience Strong knowledge of genomics, epigenetics, molecular biology, and cell biology At least 3 years of experience independently performing molecular and cell biology experiments, including tissue culture, microscopy, flow cytometry, and CRISPR-based genetic manipulation At least 2 years of experience in bioinformatic analysis of high-throughput sequencing datasets At least 2 years of experience with mass spectrometry-based proteomics Preferred Qualifications Experience mentoring undergraduate or graduate students Experience presenting research in international scientific meetings Required Documents Resume. Hiring Range $59,800 - $85,900 Per Year The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training. As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks. EEO Statement We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law. Caltech is a VEVRAA Federal Contractor. To read more Equal Employment Opportunity (EEO) go to eeoc_self_print_poster.pdf. Disability Accommodations Caltech complies with the Fair Employment and Housing Act (FEHA) and the Americans with Disabilities Act (ADA). We consider reasonable accommodation measures that may be necessary for eligible applicants and employees to perform the essential functions of a position. If you would like to request an accommodation to complete this application, interview, or otherwise participate in the employee selection process, please contact Caltech Recruiting at employment@caltech.edu. Additionally, if you do not meet the basic qualifications of a role but believe you can perform the essential functions of the job with reasonable accommodation, please reach out to Caltech Recruiting at employment@caltech.edu.