New 
Postdoctoral Research Fellow - The Anahtar Laboratory
 Mass General Physicians Organization | |
$2,080.00 - $1,561,040.00
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 United States, Massachusetts, Boston | |
| 80 Blossom Street (Show on map) | |
 Jun 17, 2026 | |
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The salary range for this position is $70,000-$71,750.
The Anahtar Laboratory in the Division of Infectious Diseases at Massachusetts General Hospital is seeking a highly motivated, creative, and collaborative postdoctoral research fellow to join our team. Our lab combines machine learning, genomics, and experimental microbiology to address the growing crisis of antimicrobial resistance, with a particular focus on discovering new antibiotic candidates and developing next-generation diagnostics for difficult-to-treat bacterial infections. The hired candidate will focus on machine learning-guided antibiotic discovery against pathogens of urgent clinical concern. We have developed and deployed deep learning models to identify structurally novel antibacterial hits against bacteria, with a focus on Neisseria gonorrhoeae. We have also applied generative AI approaches to design entirely new antibiotic scaffolds that explore uncharted regions of chemical space. We validate our computational discoveries through rigorous experimental follow-up, including MIC testing across multidrug-resistant clinical isolates, mechanism of action studies, and in vivo mouse infection models. Our lab sits at the intersection of basic research and clinical translation. Our work is directly informed by the resistant organisms, diagnostic gaps, and treatment failures we encounter clinically. We collaborate closely with engineers, clinicians, biologists, and chemists across MGH, Harvard Medical School, the Broad Institute, and MIT. Located in Boston, Massachusetts General Hospital is a Harvard Medical School-affiliated academic medical center at the forefront of biomedical research and patient care. We are committed to building an inclusive, diverse, and equitable lab environment. Recent graduates with a background in microbiology, chemistry, computer science, and/or immunology, a history of academic productivity, and excellent references are encouraged to apply. Applicants are asked to send (1) their CV, (2) a cover letter describing their background, research interests, and goals for their post-doctoral time, and (3) a PDF of a paper they have written, to Melis Anahtar (manahtar@mgh.harvard.edu). Please do not apply through this link. For more information: https://anahtarlab.mgh.harvard.edu/ Massachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. | |