Post-Doctoral Associate

Position Description

Summary:
Duties as Postdoctoral Associate will principally include the design, implementation, and interpretation of experiments aimed at elucidating the effect of phosphorylations in the function and stability of dystrophin and utrophin proteins in the context of muscular dystrophy. Also, on assisting in tension sensing and mechanotransduction projects in diverse cell lines and disease models. The Postdoctoral Associate will also participate in the day-to-day supervision of technical staff (Junior Scientists) and undergraduate students integral to achieving project goals, in drafting manuscripts that communicate the study's findings for publication in peer-reviewed manuscripts. Finally, the Postdoctoral Associate will actively participate in lab meetings and local seminars, and will represent/promote the project at relevant national meetings.

Essential Functions:
70%: Experimental design and implementation
Design and perform experiments to assess the phenotype of dystrophic mice expressing transgenic dystrophin molecules bearing disease-causing missense mutations.
10% % 10 Training/supervision of technicians and undergraduate students
Train new technical staff in standard phenotype assessment and supervise data acquisition on a day-to-day basis
15% Drafting extramural research proposals and manuscripts reporting study results
Will work with direct supervisor to plan and draft research grants to continue project as well as manuscripts reporting study results
5% Participation in seminars, journal clubs and symposia
Will present at least 1 formal seminar per year (locally or at a relevant national meeting) and attend relevant local seminars and journal clubs

Required Qualifications:
A Ph.D. in Biochemistry with first authorship on at least 1 peer-reviewed research publication. Ph.D., DDS, DVM, JD, MD or equivalent.

Preferred Qualifications:
5 years of experience with recombinant protein expression in multiple expression systems, purification and characterization, in vitro protein stability assays, muscle cell culture (including generation of transgenic lines), , biochemical and migratory analyses, as well as implementation of intracellular tension sensors and image data analysis.

BMBB:
The department of Biochemistry, Molecular Biology and Biophysics is committed to understanding the molecular mechanisms of metabolic diseases and cancer; developing novel strategies in biocatalysis and biotechnology; and advancing knowledge through structural biology and molecular biophysics. We organize ourselves into research divisions with emphases on Chemical and Structural Biology, Metabolic and Systems Biology, Molecular Biology and Synthetic Biology and Biotechnology. We are housed in new buildings with state-of-the-art research and support facilities.

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Scholarship
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost

Please visit the Office of Human Resources website for more information regarding benefits.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

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The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

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The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.